Hollywood has confronted the post-Harvey Weinstein era with a highly anticipated wear-black protest at the Golden Globes and award winners using the to praise the brave women who have spoken out against sexual harassment and gender inequality.

A-listers united behind Time's Up initiative on Sunday with the likes of Meryl Streep and Michelle Williams arriving at the ceremony in Los Angeles with gender justice activists as their guests.

Turning the Globes dark on the fashion front had been anticipated for days after a call for massive reform following the downfall of disgraced movie mogul Harvey Weinstein and numerous others in Hollywood, media, fashion, tech, publishing and other industries.

Host Seth Meyers opened the 75th annual Golden Globes by diving straight into material about the sex scandals that have roiled the industry, while a number of actresses who played strong women stepped up to claim awards.

The first award of the night went to one of Hollywood 's most powerful women, Nicole Kidman, for her performance in HBO's The Big Little Lies. Kidman dedicated her award to the “power of women”.

Other early awards continued the theme of female .

The Handmaid's Tale's Elisabeth Moss won the Golden Globe Award for best actress in a television drama. She dedicated her award to the author behind the best-selling book Margaret Atwood and the other women who have spoken up about injustices.

This year's recipient for the lifetime achievement is Oprah Winfrey, who is among the hundreds of women in the entertainment industry who have banded together to form Time's Up.

The focus at this year's Golden Globes is not on the awards themselves - but on the very powerful public debut of the Time's Up movement, an anti-sexual harassment initiative by some of Hollywood's biggest female stars.

Alison Brie said that the Time's Up initiative had made her realize how powerful women can be when they all stand together.

The advocates and activists said that their hope in walking the red carpet was to shift the focus back on survivors and solutions, and away from perpetrators of sexual misconduct.

But it's not just the ladies making a stand at the 75th annual award ceremony - many of whom will be doing so by wearing all-black ensembles - their male peers are also doing their bit to show support for the movement by donning Time's Up badges on the lapels of their tuxedos.

Justin Timberlake, Hugh Jackman, Gaten Matazarro, Finn Wolfhard, and Noah Schnapp were among dozens of leading men taking part in the movement by adding the black-and-white pins to their looks.